Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells. S. Chow, A. Unciti-Broceta, JACS Au 2022, 2, 1747–1756. [Link]
Highlighted as ‘cutting-edge’ in Bioorthogonal and Click Chemistry; curated by Prof. Carolyn R. Bertozzi
Efficient approaches for the synthesis of diverse alpha-diazo amides. S. Chow, A. Green, S. Liver, C. Arter, A. Leggott, L. Trask, G. Karageorgis, S. Warriner, A. Nelson, Synthesis, 2020, 52, 1695–1706. [Link]
Activity-directed expansion of a series of antibacterial agents. A. Leggott, J. E. Clarke, S. Chow, S. L. Warriner, A. J. O’Neill, A. Nelson, Chem. Commun., 2020, 56, 8047–8050. [Link]
Expansion of the structure–activity relationships of BACE1 inhibitors by harnessing diverse building blocks prepared using a unified synthetic approach. Joan Mayol-Llinàs, Shiao Chow, Adam Nelson. Med. Chem. Commun., 2019,10, 616-620. [Link]
Streamlining bioactive molecular discovery through integration and automation. Shiao Chow, Samuel Liver, Adam Nelson. Nature Reviews Chemistry, 2018, 2, 174–183. [Link]
Embarking on a chemical space odyssey. Shiao Y. Chow, Adam Nelson. J. Med. Chem., 2017, 60(9), 3591-3593. [Link]
Synthesis of 4H-benzo[e][1,3]oxazin-4-ones by a carbonylation–cyclization domino reaction of ortho-halophenols and cyanamide. L. Åkerbladh, S. Y. Chow, L. R. Odell, M. Larhed, ChemistryOpen, 2017, 6, 620-628. [Link]
Front Cover Issue, Highly Important
Synthesis of 11C-labeled sulfonyl carbamates through a multicomponent reaction employing sulfonyl azides, alcohols, and [11C]CO. Marc Stevens, Shiao Y. Chow, Sergio Estrada, Jonas Eriksson, Veronika Apslund, Anna Orlova, Bogdan Mitran, Gunnar Antoni, Mats Larhed, Ola Åberg, Luke R. Odell. ChemistryOpen, 2016, 5(6), 566-573. [Link]
Featured Article
Palladium-mediated 11C-carbonylations using aryl halides and cyanamide. P. Nordeman, A. Odell, S. Y. Chow, G. Antoni, L. R. Odell, Org. Biomol. Chem., 2017,15, 4875-4881. [Link]
Synthesis of sulfonyl amidines and acyl sulfonyl ureas from sulfonyl azides, carbon monoxide and amides. S. Y. Chow, L. R. Odell, J. Org. Chem., 2017, 82, 2515-2522. [Link]
Low-pressure radical [11C]-aminocarbonylation of alkyl iodides through thermal initiation. S. Y. Chow, L. R. Odell, J. Eriksson, Chem. Eur. J., 2016, 36, 5980-5989. [Link]
Mild and low-Pressure fac-Ir(ppy)3-mediated radical aminocarbonylation of unactivated alkyl iodides via visible-light photoredox catalysis. S. Y. Chow, M. Y. Stevens, L. Åkerbladh, S. Bergman, L. R. Odell, Chem. Eur. J., 2016, 22, 9155-9161. [Link]
Front Cover Issue | Cover Profile | Highly Important Article
Highlighted in ChemistryViews.
Sulfonyl azides as precursors in ligand-free palladium-catalyzed synthesis of sulfonyl carbamates and sulfonyl ureas and direct synthesis of sulfonamides. Shiao Y. Chow, Marc Y. Stevens, Luke R. Odell. J. Org. Chem., 2016, 81(7), 2681-2691. [Link]
Featured Article
Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception. Rink-Jan Lohman, Rosemary S. Harrison, Gloria Ruiz-Gomez, Huy N. Hoang, Nicholas E. Shepherd, Shiao Y. Chow, Timothy A. Hill, Praveen Madala, and David P. Fairlie. Nociceptin Opioid, Edition: 97, Chapter: 1, Elsevier (2015). [Link]
Simultaneous uncoupled expression and purification of the dengue virus NS3 protease and NS2B co-factor domain. Ashleigh Shannon, Keith Chappell, Martin Stoermer, Shiao Chow, Woan-Mei Kok, David Fairlie, Paul Young. Protein expression and purification, 2015, 119, 124-129. [Link]
Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of erk phosphorylation and thermal analgesia in mice. Rosemary S. Harrison, Gloria Ruiz-Gomez, Timothy A. Hill, Shiao Y. Chow, Nicholas E. Shepherd, Rink-Jan Lohman, Giovanni Abbenante, Huy N. Hoang, and David P. Fairlie. J. Med. Chem., 2010, 53(23), 8400–8408. [Link]
A structural and catalytic model for zinc phosphoesterases. Rebecca R. Buchholz, Morgan E. Etienne, Anneke Dorgelo, Ruth E. Mirams, Sarah J. Smith, Shiao Y. Chow, Lyall R. Hanton, Geoffrey B. Jameson, Gerhard Schenk and Lawrence R. Gahan. Dalton Trans., 2008, 43, 6045-6054. [Link]
